Uncertainty! Planning for the future when there may be no future? How do you deal with it? In the first episode of a five part documentary series, we explore these issues with two such people. Amy suffers from a form of epilepsy that potentially means she may not wake up tomorrow morning. Adriano, a fisherman on the Amazon river in Brazil, fights for survival in a changing world. His family depends on his daily catch, but the Amazon ecosystem itself is increasingly uncertain. Two different stories, both very moving. Two very different cultures, and yet the same reality: Uncertainty.